| CASE REPORT |
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| Year : 2022 | Volume
: 5
| Issue : 1 | Page : 17-21 |
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Improvement in childhood limb-girdle muscular dystrophy with Ayurvedic management: A case report
MK Lekshmi, Alka Chouhan, Anjali Sam, Rakhi Krishanan
Department of Kaumarabhrithya, Government Ayurveda College, Hospital for Women and Children, Poojappura, Thiruvananthapuram, Kerala, India
Correspondence Address:
Dr. M K Lekshmi
Department of Kaumarabhrithya Government Ayurveda College, Hospital for Women and Children, Poojappura, Thiruvananthapuram - 695 012, Kerala
India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/jacr.jacr_43_21
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The Limb-Girdle Muscular Dystrophies (LGMDs) include a heterogeneous group of disorders characterized by the progressive wasting and weakness of the proximal limb-girdle muscles. Sarcoglycanopathies are forms of LGMD that result from defect in the sarcoglycan complex. Ayurveda explains the condition in the line of Srotorodha (~obstructive pathology occurring in channels), especially at the Mamsa dhatu (~muscle tissue) level. This is the case report of an eight year old male child of autosomal recessive LGMD with no relevant family history. The patient was presented with gradual onset of proximal muscle weakness in all four limbs for two years along with pseudohypertrophy of bilateral calf muscles. He had elevated Creatine Phosphokinase (CPK) level and the genetic test findings revealed a homozygous missense variation in exon 2 of the SGCA gene. He visited the outpatient department of the tertiary Government Ayurveda Hospital and Ayurveda medications were administered along with dietary advices for two months followed by in-patient management for one month. There was a significant improvement in the clinical findings assessed by the Vignos scale of lower extremity and Barthel index along with reduction in the level of CPK value after three months of Ayurvedic management. Significant improvement in this short period of management substantiates the benefit of Ayurvedic medicines in the management of LGMD.
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